The ADREAM building consists of an innovative architectural structure which integrates 6500 sensors for the purposes of optimized systems and energy surveillance. Amid growing needs for energy optimization research and new technological developments in renewable energies, the ADREAM project stands as a prototype example for creating a multidisciplinary platform that allows the rapid progress of the Energy Networks and Smart Grid domains. A description of the ADREAM project is presented along with the energetic and control systems installed. The methodology for the development and calibration of the building's thermal model and dynamic simulation is also highlighted. The simulations are exploited for the purpose of a thermal behavior, comfort, and energy consumption analysis. The results obtained by the applied parametric variations were used for the proposition of a building renovation investment. The energy optimization goal is enhanced by the development of an ARX model for the prediction and control of energy consumptions, and a Simulink model for the global simulation of all the energetic systems.