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Communication Dans Un Congrès Année : 2016

New insight in perivenular lesion formation in multiple sclerosis on weekly susceptibility weighted images

S. Mure
  • Fonction : Auteur
T. Grenier
H. Benoit-Cattin
F. Cotton

Résumé

In this paper, we take advantage of a unique longitudinal MRI dataset acquired at weekly intervals on untreated multiple sclerosis patients. We study the signal dynamics of relapsing-remitting multiple sclerosis lesions on SWI MRI and show, thanks to an unsupervised spatiotemporal clustering algorithm, that specific signal intensity behaviors exist between the veins and the lesions that are synchronous with contrast enhancement on gadolinium-enhanced T1-weighted MRI. Our study shows that vein narrowing depicted on SWI is an early event that appears to precede blood-brain barrier disruption signified by contrast-enhancement.
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Dates et versions

hal-01452997 , version 1 (02-02-2017)

Identifiants

  • HAL Id : hal-01452997 , version 1

Citer

S. Mure, C. R. G. Guttmann, T. Grenier, H. Benoit-Cattin, F. Cotton. New insight in perivenular lesion formation in multiple sclerosis on weekly susceptibility weighted images. 24th annual meeting and exhibition ISMRM 2016, May 2016, Singapour, Singapore. pp.Abstract #1290. ⟨hal-01452997⟩
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