Elective single embryo transfer policy at 48/72 h: Which results after fresh transfers and frozen/thawed transfers? - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Gynécologie Obstétrique & Fertilité Année : 2015

Elective single embryo transfer policy at 48/72 h: Which results after fresh transfers and frozen/thawed transfers?

Résumé

Objectives. - To evaluate our elective single embryo transfer policy performed at 48/72 h and define predictive factors of pregnancy after frozen/thawed embryo transfer. Methods. - Analysis of 289 elective single embryo transfers (eSET) performed in a selected population in the ART center of Marseille University Hospital from January 2005 to December 2011, as well as the 325 following frozen/thawed embryo transfers performed in this population between May 2005 and December 2012. Results. - Cumulative pregnancy rate/oocyte retrieval was of 62.6%; 45% of the couples obtained the birth of at least one child. During this studied period, cumulative pregnancy and delivery rates in the whole population remained stable while multiple delivery rate/delivery clearly decreased. Elective single embryo after frozen/thawed transfer gave satisfying results (24.6% pregnancy/transfer) only in the lack of lysis or in case of mild lysis (1-25%) of the transferred embryo. Conclusion. - The implementation of an eSET policy gives satisfying results, depending largely on embryo quality. By proposing eSET to a well-targeted population, chosen both on clinical and biological criteria, a clear reduction of cumulative multiple delivery rate/delivery was obtained in our center over this period, without any global decrease of cumulative pregnancy rate/attempt. Embryo quality is a major factor of success, especially in frozen/thawed cycles. The elective single embryo frozen/thawed transfer should be carried out only if embryo lysis after thawing does not exceed 25%. (C) 2015 Elsevier Masson SAS. All rights reserved.
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Dates et versions

hal-01444861 , version 1 (24-01-2017)

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P. Bottin, Vincent Achard, B. Courbiere, M. Paci, A. Gnisci, et al.. Elective single embryo transfer policy at 48/72 h: Which results after fresh transfers and frozen/thawed transfers?. Gynécologie Obstétrique & Fertilité, 2015, 43 (4), pp.297--303. ⟨10.1016/j.gyobfe.2015.02.007⟩. ⟨hal-01444861⟩
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