Discovery and functional analysis of a 4th electron-transferring tryptophan conserved exclusively in animal cryptochromes and (6-4) photolyases. - Archive ouverte HAL
Article Dans Une Revue Chemical Communications Année : 2015

Discovery and functional analysis of a 4th electron-transferring tryptophan conserved exclusively in animal cryptochromes and (6-4) photolyases.

Résumé

A 4th electron transferring tryptophan in animal cryptochromes and (6-4) photolyases is discovered and functionally analyzed by transient absorption. It yields a much longer-lived flavin-tryptophan radical pair than the mere tryptophan triad in related flavoproteins, questioning the putative role of the primary light reaction of cryptochrome in animal magnetoreception.
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hal-01432183 , version 1 (11-01-2017)

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Pavel Müller, Junpei Yamamoto, Ryan Martin, Shigenori Iwai, Klaus Brettel. Discovery and functional analysis of a 4th electron-transferring tryptophan conserved exclusively in animal cryptochromes and (6-4) photolyases.. Chemical Communications, 2015, 51 (85), pp.15502-5. ⟨10.1039/c5cc06276d⟩. ⟨hal-01432183⟩
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