Identification of Atg8 from Acanthamoeba castellanii by genetic complementation in Saccharomyces cerevisiae. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Molecular and Biochemical Parasitology Année : 2016

Identification of Atg8 from Acanthamoeba castellanii by genetic complementation in Saccharomyces cerevisiae.

Résumé

Autophagy is a eukaryotic process responsible for the degradation of intracellular content such as damaged organelles. Several putative autophagy-related genes have been identified within the annotated genome of the free-living amoeba Acanthamoeba castellanii. However, the involvement of the corresponding proteins in the autophagy pathway had not been formerly established. Here, we report that AcAtg8 cDNA can complement ATG8-deficient Saccharomyces cerevisiae.
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Dates et versions

hal-01427910 , version 1 (06-01-2017)

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Matthieu Régnacq, Pierre Voisin, Yann Héchard, Thierry Bergès, Christine Braquart-Varnier, et al.. Identification of Atg8 from Acanthamoeba castellanii by genetic complementation in Saccharomyces cerevisiae.. Molecular and Biochemical Parasitology, 2016, 210 (1-2), pp.55-57. ⟨10.1016/j.molbiopara.2016.08.006⟩. ⟨hal-01427910⟩
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