Manganese(III) Acetate-mediated Oxidative Cyclization of alpha-Methylstyrene and trans-Stilbene with beta-Ketosulfones - Archive ouverte HAL
Article Dans Une Revue Molecules Année : 2013

Manganese(III) Acetate-mediated Oxidative Cyclization of alpha-Methylstyrene and trans-Stilbene with beta-Ketosulfones

Résumé

A convenient microwave irradiation protocol was utilized for the synthesis of beta-ketosulfones 1–5 in good yields. These sulfones reacted with alkenes through a radical oxidative cyclization mediated by Mn(OAc) 3. Dihydrofurans 6–10 were obtained in moderate to good yields starting from 1,1-disubstituted alkenes. Dihydrofurans 11–15 were synthesized in moderate yields and unexpected cyclopropanes 16–19 were obtained in low yields starting from 1,2-disubstituted alkenes. This protocol offers access to various dihydrofurans which could be tested for their antiparasitic potential.

Domaines

Chimie organique
Fichier principal
Vignette du fichier
molecules-2013.pdf (368.96 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-01423378 , version 1 (29-12-2016)

Identifiants

Citer

Ahlem Bouhlel, Christophe Curti, Clémence Tabelé, Patrice Vanelle. Manganese(III) Acetate-mediated Oxidative Cyclization of alpha-Methylstyrene and trans-Stilbene with beta-Ketosulfones. Molecules, 2013, 2013, pp.4293 - 4307. ⟨10.3390/molecules18044293⟩. ⟨hal-01423378⟩
28 Consultations
343 Téléchargements

Altmetric

Partager

More