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Communication Dans Un Congrès Année : 2016

Efficient Population-Representative Whole-Cortex Parcellation Based on Tractography

Résumé

The human brain is arranged in areas based on criteria such as cytoarchitecture or extrinsic connectivity. Current hypotheses attribute specialized functions to several areas of this patchwork. Hence, parcellating the cortex into such areas and characterizing their interaction is key to understanding brain function. Diffusion MRI enables the exploration of physical connections through axonal bundles, namely extrinsic connectivity. Current theories hold that brain function is determined by extrinsic connectivity. However, obtaining a population-representative parcellation based on extrinsic connectivity remains challenging (Jbabdi 2013). Particularly, whole-cortex parcellation methods (Moreno-Dominguez 2014; Parisot 2015) are computationally expensive and need tuning of several parameters. Our main contribution is an efficient technique to create single-subject and population-representative parcellations based on tractography. Our method creates a dendrogram using only one parameter: the minimum size of each parcel. Then, by choosing cutting criteria, we can explore different parcellation granularities without recomputing the dendrogram. Experiments show that our parcellations are consistent within subjects with anatomical (Desikan 2006) and functional (Barch 2013) parcellations existent in the literature.

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Imagerie
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Dates et versions

hal-01408881 , version 1 (05-12-2016)
hal-01408881 , version 2 (11-01-2017)

Identifiants

  • HAL Id : hal-01408881 , version 1

Citer

Guillermo Gallardo-Diez, Rachid Deriche, Demian Wassermann. Efficient Population-Representative Whole-Cortex Parcellation Based on Tractography. Organization for Human Brain Mapping (OHBM)., Jun 2016, Geneva, Switzerland. ⟨hal-01408881v1⟩
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