Maternal high dietary linoleic acid during gestation and lactation impairs rat offspring gut and metabolic homeostasis - Archive ouverte HAL Access content directly
Conference Papers Year : 2016

Maternal high dietary linoleic acid during gestation and lactation impairs rat offspring gut and metabolic homeostasis

Charlène Alain
  • Function : Author
Justine Marchix
Sandrine David
  • Function : Author
Cécile Druart
  • Function : Author
N. Delzenne
  • Function : Author
Gaëlle Boudry

Abstract

Linoleic acid (LA) consumption has increased over the last decades. This polyunsaturated fatty acid (PUFA) can be metabolized in various bioactive molecules that might impact gut barrier function, gut microbiota and lipid metabolism. Our objective was to assess if dietary LA excessive consumption during gestation and lactation affect offspring gut ecology and barrier function and lipid metabolism in a rat model.
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Dates and versions

hal-01406535 , version 1 (01-12-2016)

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  • HAL Id : hal-01406535 , version 1

Cite

Charlène Alain, Justine Marchix, Sandrine David, Frédérique Barloy-Hubler, Cécile Druart, et al.. Maternal high dietary linoleic acid during gestation and lactation impairs rat offspring gut and metabolic homeostasis. 49. Annual meeting of the european society for paediatric gastroenterology, hepatology and nutrition (ESPGHAN), 2016, Athènes, Greece. pp.654. ⟨hal-01406535⟩
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