Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
Résumé
Biomimetic nanoparticles prepared by self-assembly of iminosugar-based glycopolypeptides evidenced remarkablemultivalency properties when inhibiting alpha-mannosidase activity. This approach paves the way to obtain biologically active drug delivery systems having glycosidase inhibition potency.