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Article Dans Une Revue Global Journal of Pure and Applied Chemistry Research Année : 2016

SYNTHESIS OF NEW HIGHER HOMOLOGUES OF QUISQUALIC ACID

Résumé

The compounds such as methyl 2-(tert-butoxycarbonyl)-4-(3,5-dioxo-4-phenyl-1,2,4-oxadiazolidin-2-yl)butanoate and 2-amino-4-(3,5-dioxo-4-phenyl-1,2,4-oxadiazolidin-2-yl)butanoic acid, higher homologues of quisqualic acid, have been synthesized in a first time via N-alkylation reaction of 4-phenyl-1,2,4-oxadiazolidine-3,5-dione by alkyl 2-(tert-butoxycarbonyl)-4-iodobutanoate in presence of potassium carbonate as base in dry acetone. The structures of the synthesized compounds were established by 1 H-NMR, MS data and elemental analysis.

Domaines

Chimie organique
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Dates et versions

hal-01367579 , version 1 (25-06-2020)

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  • HAL Id : hal-01367579 , version 1

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Anouar Alami, Younas Aouine, Hassane Faraj, Abdelilah El Hallaoui, Brahim Labriti, et al.. SYNTHESIS OF NEW HIGHER HOMOLOGUES OF QUISQUALIC ACID. Global Journal of Pure and Applied Chemistry Research , 2016, 4 (2), pp.1-4. ⟨hal-01367579⟩
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