In order to increase the realism of medical simulators, haptic interfaces could be used to simulate the patient’s body behavior. It is especially interesting to reproduce the stiffness of different soft tissues with corresponding haptic behaviors. In this paper, two control laws, impedance control and back-stepping associated with a closed-loop stiffness tuning, are introduced and applied to a pneumatic actuator. Both controllers have been obtained by using the A-T transform which is suitable to model the behavior of a pneumatic system, in a strict-feedback form. Both control laws allow to tune the system stiffness. A comparison of their performances is presented, based on experimental results.