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Article Dans Une Revue PLoS ONE Année : 2012

Attributable causes of esophageal cancer incidence and mortality in China

J. B. Wang
  • Fonction : Auteur
J. H. Fan
  • Fonction : Auteur
H. Liang
  • Fonction : Auteur
J. Li
  • Fonction : Auteur
H. J. Xiao
  • Fonction : Auteur
W. Q. Wei
  • Fonction : Auteur
S. M. Dawsey
  • Fonction : Auteur
Y. L. Qiao
  • Fonction : Auteur

Résumé

BACKGROUND: To estimate the contribution of tobacco smoking, alcohol drinking, low vegetable intake and low fruit intake to esophageal cancer mortality and incidence in China. METHODOLOGY/PRINCIPAL FINDINGS: We calculated the proportion of esophageal cancer attributable to four known modifiable risk factors [population attributable fraction (PAF)]. Exposure data was taken from meta-analyses and large-scale national surveys of representative samples of the Chinese population. Data on relative risks were also from meta-analyses and large-scale prospective studies. Esophageal cancer mortality and incidence came from the 3(rd) national death cause survey and population-based cancer registries in China. We estimated that 87,065 esophageal cancer deaths (men 67,686; women: 19,379) and 108,206 cases (men: 83,968, women: 24,238) were attributable to tobacco smoking, alcohol drinking, low vegetable intake and low fruit intake in China in 2005. About 17.9% of esophageal cancer deaths among men and 1.9% among women were attributable to tobacco smoking. About 15.2% of esophageal cancer deaths in men and 1.3% in women were caused by alcohol drinking. Low vegetable intake was responsible for 4.3% esophageal cancer deaths in men and 4.1% in women. The fraction of esophageal cancer deaths attributable to low fruit intake was 27.1% in men and 28.0% in women. Overall, 46% of esophageal cancers (51% in men and 33% in women) were attributable to these four modifiable risk factors. CONCLUSIONS/SIGNIFICANCE: Tobacco smoking, alcohol drinking, low vegetable intake and low fruit intake were responsible for 46% of esophageal cancer mortality and incidence in China in 2005. These findings provide useful data for developing guidelines for esophageal cancer prevention and control in China.

Dates et versions

hal-01262947 , version 1 (27-01-2016)

Identifiants

Citer

J. B. Wang, J. H. Fan, H. Liang, J. Li, H. J. Xiao, et al.. Attributable causes of esophageal cancer incidence and mortality in China. PLoS ONE, 2012, 7 (8), pp.e42281. ⟨10.1371/journal.pone.0042281⟩. ⟨hal-01262947⟩

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