The concept of sustainability was developed in order to improve the present human living standards while maintaining the availability of the natural resources for future generations. According to this definition, technological development is a way to improve the sustainability, because it enables to meet human needs by transforming natural resources into useful products. By 2050, the urban world population is expected to approximately double to an estimated 6.4 billion2 and we are aware that the Earth’s natural resources are already limited. In this context, less impacting and more efficient industrial processes’ design represents a real challenge for engineers. From now on, the impacts of new technologies have to be assessed in detail, all along their life cycle, even before their massive industrial deployment.We should be sure that the generated impacts are actually counterbalanced by the improvement of the living standards on Earth. In this chapter, we will consider new technologies related to the development and treatment of lithium batteries. In the first part, we will demonstrate how existing studiesare already taking into account environmental impacts assessment and we will particularly emphasize the main assumptions realized using life cycle assessment (LCA) approaches. In the second part, we will focus on the end-of-life (EOL) of lithium batteries to demonstrate that the entire value chain has to be considered while arbitrating on the acceptability or not of a design decision from an environmental perspective.