External reliability in data-center networking is today commonly reached via forms of provider multihoming, so as to guarantee higher service availability rates. In parallel, Cloud users also resort to multihoming via different device access interfaces (Wi-fi, 3G, Wired). Both practices add path diversity between Cloud users and servers, unusable with legacy communication protocols. To overcome this void, we present a holistic multipath communication architecture for Cloud access and inter-Cloud communications, and defend its possible implementation using three promising recent protocols functionally acting at three different communication layers: MPTCP, LISP and TRILL.