A straightforward synthesis of unsymmetrical secondary phosphine boranes - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Green Chemistry Année : 2010

A straightforward synthesis of unsymmetrical secondary phosphine boranes

Résumé

A one-pot procedure for the synthesis of unsymmetrical alkyl-substituted secondary phosphine oxides is described. The sequential addition of N-benzylaniline to a solution of dichlorophenylphosphine and 1-methylimidazole in methylcyclohexane, separating of the protic ionic liquid formed, addition of Grignard reagent followed by hydrolysis gave unsymmetrical secondary phosphine oxides (SPOs) in high yield. The use of ionic liquids in the first step is essential and streamlined the synthesis. Unsymmetrical SPOs could be quantitatively reduced to secondary phosphine using a catalytic amount of Ti(OiPr)4 and tetramethyldisiloxane (TMDS) under mild reaction conditions.

Domaines

Chimie organique

Dates et versions

hal-01166243 , version 1 (22-06-2015)

Identifiants

Citer

Christelle Petit, Alain Favre-Réguillon, Gérard Mignanic, Marc Lemaire. A straightforward synthesis of unsymmetrical secondary phosphine boranes. Green Chemistry, 2010, 12, pp.326-330. ⟨10.1039/b920324a⟩. ⟨hal-01166243⟩
31 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More