Selective trifluoromethylthiolation of heteroaromatic sp2 C-H bonds with the 2nd generation of trifluoromethanesulfenamide reagent
Résumé
By applying a well-established protocol of selective deprotonation of heteroarenes, the selective trifluoromethylthiolation of various heteroaromatic compounds has been performed, by using the 2nd generation of trifluoromethanesulfenamide reagent. With such strategy, functionalized heteroarenes could be synthesized as potential trifluoromethylthiolated building-blocks.