ULPC-MS/MS phenolic quantification and in vitro anticancer potential of Gmelina arborea Roxb. (Verbenaceae) - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Der Chemica Sinica Année : 2014

ULPC-MS/MS phenolic quantification and in vitro anticancer potential of Gmelina arborea Roxb. (Verbenaceae)

Résumé

Phenolic secondary metabolites are recognized as excellent antioxidants and are subject of numerous scientific studies. The present study was aimed firstly, to quantify the phenolic constituents contained in the hydroacetonic crude extract obtained from Gmelina arborea leaves by UPLC-MS/MS and secondly, to investigate in vitro its anticancer potential against 6 cancerous cell lines. The quantitative analysis revealed a significant abundance in flavonoids (75.50%) and a presence of hydroxycinnamic acid derivatives (24.49%). The results of cytotoxicity survey clearly indicate that the hydroacetonic crude extract shows a good anticancer activity against C6 glioma cells.

Domaines

Chimie
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Dates et versions

hal-01138926 , version 1 (03-04-2015)

Identifiants

  • HAL Id : hal-01138926 , version 1
  • PRODINRA : 312856

Citer

K C.C. N'Gaman, Gui Roger M. Kabran, Amani Kadja, J A Mamyrbékova-Békro, Jean-Luc Pirat, et al.. ULPC-MS/MS phenolic quantification and in vitro anticancer potential of Gmelina arborea Roxb. (Verbenaceae). Der Chemica Sinica, 2014, Pelagia Research Library, 5 (6), pp.13-17. ⟨hal-01138926⟩
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