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Article Dans Une Revue ACS Sustainable Chemistry & Engineering Année : 2014

Facile Ecofriendly Synthesis of Monastrol and Its Structural Isomers via Biginelli Reaction

Résumé

In this paper, a Q-tube equipment is proposed as a valid alternative to monomode MW technology to synthesize in a simple and economic way a library of dihydropyrimidine derivatives performing the Biginelli reaction in solvent-free conditions under pressure and with the catalysis of a very mild and environmentally benign Lewis acid consisting of erbium trichloride hexahydrate.
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hal-01121382 , version 1 (28-02-2015)

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Manuela Oliverio, Paola Costanzo, Monica Nardi, Ivan Rivalta, Antonio Procopio. Facile Ecofriendly Synthesis of Monastrol and Its Structural Isomers via Biginelli Reaction. ACS Sustainable Chemistry & Engineering, 2014, 2 (5), pp.1228-1233. ⟨10.1021/sc5000682⟩. ⟨hal-01121382⟩
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