The Internet of Things (IoT) is a paradigm in which smart objects actively collaborate among them and with other physical and virtual objects available in the Web in order to perform high-level tasks for the benefit of end-users. In the e-health scenario, these communicating smart objects can be body sensors that enable a continuous real-time monitoring of vital signs of patients. Data produced by such sensors can be used for several purposes and by different actors, such as doctors, patients, relatives, and health care centers, in order to provide remote assistance to users. However, major challenges arise mainly in terms of the interoperability among several heterogeneous devices from a variety of manufacturers. In this context, we introduce EcoHealth (Ecosystem of Health Care Devices), a Web middleware platform for connecting doctors and patients using attached body sensors, thus aiming to provide improved health monitoring and diagnosis for patients. This platform is able to integrate information obtained from heterogeneous sensors in order to provide mechanisms to monitor, process, visualize, store, and send notifications regarding patients’ conditions and vital signs at real-time by using Internet standards. In this paper, we present blueprints of our proposal to EcoHealth and its logical architecture and implementation, as well as an e-health motivational scenario where such a platform would be useful.