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Communication Dans Un Congrès Année : 2012

Topaz1 is essential for spermatogenesis and male fertility

Résumé

Knockout of Topaz1 in mice results in male sterility with no post-meiotic spermatids or spermatozoa. Expression of most of genes involved in the PIWI pathway, DNA methylation and retrotransposons silencing will be investigated. The high degree of TOPAZ1 conservation in vertebrates and the presence of its protein in germline stimulate our interest to determine the essential role of Topaz1 in mouse.
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Dates et versions

hal-01019621 , version 1 (07-07-2014)

Identifiants

  • HAL Id : hal-01019621 , version 1
  • PRODINRA : 254879

Citer

Alix Luangpraseuth, Adrienne Baillet, Elodie Poumerol, Corinne Cotinot, Béatrice Mandon-Pepin. Topaz1 is essential for spermatogenesis and male fertility. 17. Eurpean Workshop on Molecular and Cellular Endocrinology on the Testis, European Society for Sexual Medicine (ESSM). ITA.; Institut Curie. FRA., Apr 2012, Stockholm, Sweden. 1 p. ⟨hal-01019621⟩
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