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Welcome to the BREED publications collection
The Biology of Reproduction, Environment, Epigenetics and Development (BREED) joint research unit studies the effects of environment, in the broadest sense, on reproduction, development during embryonic and foetal life and the health of offspring. It gathers researchers, hospital clinicians and veterinarians for both agronomic and biomedical research.
The scientific context is based on the need to understand and control the mechanisms of epigenetic programming during prenatal life leading to the birth of a healthy, fertile and robust individual, capable of adapting to changes in its environment.
The aims of our research are to improve fertility and the efficiency of reproductive biotechnologies in humans and animals, to study the physiological and molecular mechanisms that determine the phenotypes of the offspring (health, growth, fertility, etc.) and to identify predictive and non-invasive biomarkers for these phenotypes, some of which could complement genetic selection strategies in animals. The unit relies on research involving several animal models (rabbits, ruminants, rodents, horses) and multiple and complementary imaging approaches, from the microscopic scale to the whole live animal. In vitro models are also developed as alternatives to animal experimentation (primary cell cultures, organoids, embryoids). This expertise and tools are complemented by clinical studies conducted by hospital and veterinary practitioners.
Last additions
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Dorothee Ledoux, Isabelle Veissier, Bruno Meunier, Valerie Gelin, Christophe Richard, et al.. Combining accelerometers and direct visual observations to detect sickness and pain in cows of different ages submitted to systemic inflammation. Scientific Reports, 2023, 13 (1), pp.1977. ⟨10.1038/s41598-023-27884-x⟩. ⟨hal-03975769⟩
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Ophélie Téteau, Anaïs Vitorino Carvalho, Pascal Papillier, Béatrice Mandon-Pepin, Luc Jouneau, et al.. Bisphenol A and bisphenol S both disrupt ovine granulosa cell steroidogenesis but through different molecular pathways. Journal of Ovarian Research, 2023, 16 (1), pp.30. ⟨10.1186/s13048-023-01114-4⟩. ⟨hal-03972669⟩
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Elodie Merlot, Caroline Clouard, Mariana Mescouto Lopes, Déborah Ménard, Caroline Hervet, et al.. Influence du logement et des caractéristiques sociales maternelles pendant la gestation sur les fonctions des monocytes des porcelets. 6ème colloque de la SF-DOHaD, Nov 2023, Rennes, France. ⟨hal-04292632⟩
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Matthieu Glorion, Florentina Pascale, Maxime Huriet, Jérôme Estephan, Carla Gouin, et al.. Differential early response of monocyte/macrophage subsets to intra-operative corticosteroid administration in lung transplantation. Frontiers in Immunology, 2023, 14, ⟨10.3389/fimmu.2023.1281546⟩. ⟨hal-04311493⟩
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Aurélie Nicolas, Martine Deplanche, Sandrine Péron, Pierre-Henri Commere, Alan Diot, et al.. Unveiling the Secrets of Long-Term Staphylococcus aureus Infections: Insights into Inflammation, Metabolism, and Epigenetic Changes from Non-Immune Cells Transcriptomes. Rendez-vous scientifique annuel d’Op+lait Réunion glande Mammaire lait, Galactinov, Réseau Oplait-Galctinov, Oct 2023, Québec (online), Canada. ⟨hal-04251786⟩
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Delphine Lallias, Elodie Harté, Michaël Marchand, Aurélie Chaulot-Talmon, Anne Frambourg, et al.. IMPACT OF EARLY COLD TEMPERATURE ON GENOMEWIDE DNA METHYLATION PATTERNS IN JUVENILE RAINBOW TROUT DIVERGENT LINES FOR MUSCLE FAT CONTENT. Aquaculture Europe, European Aquaculture Society (EAS), Sep 2023, Vienna, Austria. ⟨10.15454/1.5572329612068406E12⟩. ⟨hal-04256745⟩
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References
2 174
Open Access
33 %
Keywords
Ruminant
Souris
Methylation
Ovaire
Trophoblast
Embryo transfer
Sperm
Gestation
Méthylation
Adult
Oocyte
Développement
Épigénétique
Diesel
Infertility
Horse
Epigenetic
Cattle
Male
Métabolisme
Alimentation
Foetus
Meiosis
Female
Environment
Fertility
GENOMIQUE
Mammary gland
Epigenetics
Animal model
Programmation foetale
Animal models
Implantation
Obésité
NUCLEAR TRANSFER
Nutrition
Somatic cell nuclear transfer
Programming
IMMUNOLOGIE
Développement embryonnaire
Epigénétique
Fertilité
Pluripotency
Pregnancy
Embryon
Bovine
Rabbit
PLACENTA
Mare
Sheep
IMAGE
Mice
These
BIOLOGIE DU DEVELOPPEMENT
Dna methylation
Goat
Embryo
Reproduction
Mouse
Inflammation
Foxl2
Gene expression
Phénotype
Conceptus
Ovary
Cheval
Spermatogenesis
Growth
RAT
Bovin
BIOTECHNOLOGIE
Embryo development
Obesity
Nuclear transfer
Dairy cow
Sex determination
Animal modèle
Endomètre
Humans
Equine
Fetal programming
Lapin
Placenta
Endometrium
Oxidative stress
Jument
Chorion
Male infertility
Transcriptome
DNA methylation
IMAGERIE
Progesterone
Dohad
Uterus
GENETIQUE
DOHaD
Development
Sexual dimorphism
Poulain
EMBRYO