Loading...
Welcome to the BREED publications collection
The Biology of Reproduction, Environment, Epigenetics and Development (BREED) joint research unit studies the effects of environment, in the broadest sense, on reproduction, development during embryonic and foetal life and the health of offspring. It gathers researchers, hospital clinicians and veterinarians for both agronomic and biomedical research.
The scientific context is based on the need to understand and control the mechanisms of epigenetic programming during prenatal life leading to the birth of a healthy, fertile and robust individual, capable of adapting to changes in its environment.
The aims of our research are to improve fertility and the efficiency of reproductive biotechnologies in humans and animals, to study the physiological and molecular mechanisms that determine the phenotypes of the offspring (health, growth, fertility, etc.) and to identify predictive and non-invasive biomarkers for these phenotypes, some of which could complement genetic selection strategies in animals. The unit relies on research involving several animal models (rabbits, ruminants, rodents, horses) and multiple and complementary imaging approaches, from the microscopic scale to the whole live animal. In vitro models are also developed as alternatives to animal experimentation (primary cell cultures, organoids, embryoids). This expertise and tools are complemented by clinical studies conducted by hospital and veterinary practitioners.
Last additions
-
Dorothee Ledoux, Isabelle Veissier, Bruno Meunier, Valerie Gelin, Christophe Richard, et al.. Combining accelerometers and direct visual observations to detect sickness and pain in cows of different ages submitted to systemic inflammation. Scientific Reports, 2023, 13 (1), pp.1977. ⟨10.1038/s41598-023-27884-x⟩. ⟨hal-03975769⟩
-
Ophélie Téteau, Anaïs Vitorino Carvalho, Pascal Papillier, Béatrice Mandon-Pepin, Luc Jouneau, et al.. Bisphenol A and bisphenol S both disrupt ovine granulosa cell steroidogenesis but through different molecular pathways. Journal of Ovarian Research, 2023, 16 (1), pp.30. ⟨10.1186/s13048-023-01114-4⟩. ⟨hal-03972669⟩
-
-
-
Mariana Mescouto Lopes, Caroline Clouard, Jennifer Chambeaud, Manon Brien, Nicolas Villain, et al.. Impact of environmental enrichment on the behaviour and immune cell transcriptome of pregnant sows. 74. Annual meeting of the european federation of animal science (EAAP), INRAE; EAAP, Aug 2023, Lyon, France. pp.887. ⟨hal-04207105⟩
-
-
-
-
-
Laurent Galio, Laetitia Bernet, Yoann Rodriguez, Camille Fourcault, Marie‐noëlle Dieudonné, et al.. The effect of obesity on uterine receptivity is mediated by endometrial extracellular vesicles that control human endometrial stromal cell decidualization and trophoblast invasion. Journal of Extracellular Biology, 2023, 2 (7), ⟨10.1002/jex2.103⟩. ⟨hal-04165774⟩
-
Rossella Cannarella, Rupin Shah, Taha Abo-Almagd Abdel-Meguid Hamoda, Florence Boitrelle, Ramadan Saleh, et al.. Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data. The World Journal of Men's Health, 2023, 41, ⟨10.5534/wjmh.230034⟩. ⟨hal-04149299⟩
-
-
-
Mahendra Mariadassou, Laurent-Xavier Nouvel, Fabienne Constant, Diego P. Morgavi, Lucie Rault, et al.. Microbiota members from body sites of dairy cows are largely shared within individual hosts throughout lactation but sharing is limited in the herd. Animal Microbiome, 2023, 5 (1), pp.32. ⟨10.1186/s42523-023-00252-w⟩. ⟨hal-04126196⟩
-
Mahendra Mariadassou, Laurent X Nouvel, Fabienne Constant, Diego P Morgavi, Lucie Rault, et al.. Microbiota members from body sites of dairy cows are largely shared within individual hosts throughout lactation but sharing is limited in the herd. Animal Microbiome, 2023, 5 (32), pp.1-17. ⟨10.1186/s42523-023-00252-w⟩. ⟨hal-04204329⟩
-
E. Ivanova, Catherine Hue-Beauvais, Aurélie Chaulot-Talmon, J. Castille, J Laubier, et al.. DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part I – the impact of inflammation. Epigenetics, 2023, 18 (1), ⟨10.1080/15592294.2023.2215633⟩. ⟨hal-04127637⟩
References
2 151
Open Access
32 %
Keywords
IMAGERIE
Obésité
Gestation
Animal models
Foxl2
Female
Goat
Blastocyst
BIOTECHNOLOGIE
Oocyte
Programmation foetale
Embryo
Environment
NUCLEAR TRANSFER
Animal modèle
Ruminant
Développement embryonnaire
Epigénétique
Foetus
Reproduction
Chorion
Jument
Horse
Ovaire
Methylation
These
Growth
Conceptus
Développement
Diesel
Dohad
Male infertility
Infertility
Uterus
Programming
Dna methylation
Ovary
Sperm
Embryon
Pregnancy
Transcriptome
Epigenetic
Animal model
Adult
Cheval
Méthylation
Spermatogenesis
BIOLOGIE DU DEVELOPPEMENT
IMMUNOLOGIE
Trophoblast
Sex determination
Epigenetics
Fertility
Dairy cow
Placenta
Embryo transfer
Implantation
EMBRYO
Fertilité
GENETIQUE
Mice
Rabbit
Poulain
Bovine
Equine
RAT
Development
Endomètre
Nutrition
Alimentation
Embryo development
Pluripotency
Progesterone
Mare
Meiosis
Somatic cell nuclear transfer
PLACENTA
Obesity
Gene expression
Phénotype
Mammary gland
Oxidative stress
Souris
GENOMIQUE
Bovin
Cattle
Nuclear transfer
Male
Sexual dimorphism
Métabolisme
IMAGE
Humans
DOHaD
Sheep
Épigénétique
Lapin
Fetal programming
DNA methylation
Mouse
Endometrium