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Journal Articles Journal of Computational Biology Year : 2014

Easy identification of generalized common and conserved nested intervals

Abstract

In this paper we explain how to easily compute gene clusters, formalized by classical or generalized nested common or conserved intervals, between a set of K genomes represented as K permutations. A b-nested common (resp. conserved) interval I of size |I| is either an interval of size 1 or a common (resp. conserved) interval that contains another b-nested common (resp. conserved) interval of size at least |I|-b. When b=1, this corresponds to the classical notion of nested interval. We exhibit two simple algorithms to output all b-nested common or conserved intervals between K permutations in O(Kn+nocc) time, where nocc is the total number of such intervals. We also explain how to count all b-nested intervals in O(Kn) time. New properties of the family of conserved intervals are proposed to do so.

Dates and versions

hal-00921762 , version 1 (21-12-2013)

Identifiers

Cite

Fabien de Montgolfier, Mathieu Raffinot, Irena Rusu. Easy identification of generalized common and conserved nested intervals. Journal of Computational Biology, 2014, 21 (7), pp.520-533. ⟨10.1089/cmb.2013.0146⟩. ⟨hal-00921762⟩
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