Crohn's disease of the vulva. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Crohn's and Colitis Année : 2013

Crohn's disease of the vulva.

Résumé

: Crohn's disease (CD) of the vulva is a rare, yet under recognized condition. Fistulae arising from the digestive tract account for the greater part of genital lesions in CD. However, cutaneous so-called metastatic lesions of the vulva have been reported in the literature. They are clinically challenging for gastroenterologists as well as for gynecologists, with numerous differential diagnoses, especially among venereal diseases, and require a multidisciplinary approach. The most frequently observed features of the disease are labial swelling, vulvar ulcers, and hypertrophic lesions. Biopsy samples for histological study are mandatory, in order to establish the diagnosis of vulvar CD. Treatment options include oral prolonged courses of metronidazole and systemic immunosuppressive therapy such as corticosteroids and azathioprine, with promising data published on the efficacy of infliximab. Surgery remains restricted to medical treatment failures or resection of unsightly lesions. Prospective studies or case series with long follow-up data are still missing to guide the treatment of this condition.

Domaines

Chimie organique

Dates et versions

hal-00907293 , version 1 (21-11-2013)

Identifiants

Citer

Maximilien Barret, Vincent de Parades, Maxime Battistella, Harry Sokol, Nicolas Lemarchand, et al.. Crohn's disease of the vulva.. Journal of Crohn's and Colitis, 2013, 10, pp.563-570. ⟨10.1016/j.crohns.2013.10.009⟩. ⟨hal-00907293⟩
132 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More