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Article Dans Une Revue Genetics Selection Evolution Année : 2005

A comparison of two methods for prediction of response and rates of inbreeding in selected populations with the results obtained in two selection experiments

Valérie Loywyck
  • Fonction : Auteur
Piter Bijma
  • Fonction : Auteur
Marie-Hélène Pinard-van Der Laan
Johan van Arendonk
  • Fonction : Auteur
Etienne Verrier
  • Fonction : Auteur

Résumé

Selection programmes are mainly concerned with increasing genetic gain. However, short-term progress should not be obtained at the expense of the within-population genetic variability. Different prediction models for the evolution within a small population of the genetic mean of a selected trait, its genetic variance and its inbreeding have been developed but have mainly been validated through Monte Carlo simulation studies. The purpose of this study was to compare theoretical predictions to experimental results. Two deterministic methods were considered, both grounded on a polygenic additive model. Differences between theoretical predictions and experimental results arise from differences between the true and the assumed genetic model, and from mathematical simplifications applied in the prediction methods. Two sets of experimental lines of chickens were used in this study: the Dutch lines undergoing true truncation mass selection, the other lines (French) undergoing mass selection with a restriction on the representation of the different families. This study confirmed, on an experimental basis, that modelling is an efficient approach to make useful predictions of the evolution of selected populations although the basic assumptions considered in the models (polygenic additive model, normality of the distribution, base population at the equilibrium, etc.) are not met in reality. The two deterministic methods compared yielded results that were close to those observed in real data, especially when the selection scheme followed the rules of strict mass selection: for instance, both predictions overestimated the genetic gain in the French experiment, whereas both predictions were close to the observed values in the Dutch experiment.
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hal-00894500 , version 1 (11-05-2020)

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  • HAL Id : hal-00894500 , version 1

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Valérie Loywyck, Piter Bijma, Marie-Hélène Pinard-van Der Laan, Johan van Arendonk, Etienne Verrier. A comparison of two methods for prediction of response and rates of inbreeding in selected populations with the results obtained in two selection experiments. Genetics Selection Evolution, 2005, 37 (3), pp.273-289. ⟨hal-00894500⟩
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