Time-resolved diffuse optical tomography using fast-gated single-photon avalanche diodes - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Biomedical optics express Année : 2013

Time-resolved diffuse optical tomography using fast-gated single-photon avalanche diodes

Résumé

We present the first experimental results of reflectance Diffuse Optical Tomography (DOT) performed with a fast-gated single-photon avalanche diode (SPAD) coupled to a time-correlated single-photon counting system. The Mellin-Laplace transform was employed to process time-resolved data. We compare the performances of the SPAD operated in the gated mode vs. the non-gated mode for the detection and localization of an absorbing inclusion deeply embedded in a turbid medium for 5 and 15 mm interfiber distances. We demonstrate that, for a given acquisition time, the gated mode enables the detection and better localization of deeper absorbing inclusions than the non-gated mode. These results obtained on phantoms demonstrate the efficacy of time-resolved DOT at small interfiber distances. By achieving depth sensitivity with limited acquisition times, the gated mode increases the relevance of reflectance DOT at small interfiber distance for clinical applications.

Dates et versions

hal-00873584 , version 1 (16-10-2013)

Identifiants

Citer

A. Puszka, L. Di Sieno, A. Dalla Mora, A. Pifferi, D. Contini, et al.. Time-resolved diffuse optical tomography using fast-gated single-photon avalanche diodes. Biomedical optics express, 2013, 4 (8), pp.1351-1365. ⟨10.1364/BOE.4.001351⟩. ⟨hal-00873584⟩
58 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More