This chapter discusses the necessary conditions for the successful design of a driving simulator. This success is assessed, among other factors, by the quality of the rendered motions, when driving the simulator. We discuss throughout this chapter, the philosophy of driving simulation to better explain the challenges of these applications. Particular attention will be paid to the interaction between the various entities, making up a simulation system operational. This interaction is intended to highlight the importance of mechatronics in the successful design of such a simulator.