Enzyme-Catalyzed Oxidation Facilitates the Return of Fluorescence for Single-Walled Carbon Nanotubes. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of the American Chemical Society Année : 2013

Enzyme-Catalyzed Oxidation Facilitates the Return of Fluorescence for Single-Walled Carbon Nanotubes.

Cheuk Fai Chiu
  • Fonction : Auteur
Brian A Barth
  • Fonction : Auteur
Gregg P Kotchey
  • Fonction : Auteur
Yong Zhao
  • Fonction : Auteur
Kristy A Gogick
  • Fonction : Auteur
Wissam A Saidi
  • Fonction : Auteur
Stéphane Petoud
Alexander Star
  • Fonction : Auteur

Résumé

In this work, we studied enzyme-catalyzed oxidation of single-walled carbon nanotubes (SWCNTs) produced by the high-pressure carbon monoxide (HiPco) method. While oxidation via strong acids introduced defect sites on SWCNTs and suppressed their near-infrared (NIR) fluorescence, our results indicated that the fluorescence of SWCNTs was restored upon enzymatic oxidation, providing new evidence that the reaction catalyzed by horseradish peroxidase (HRP) in the presence of H2O2 is mainly a defect-consuming step. These results were further supported by both UV-vis-NIR and Raman spectroscopy. Therefore, when acid oxidation followed by HRP-catalyzed enzyme oxidation was employed, shortened (<300 nm in length) and NIR-fluorescent SWCNTs were produced. In contrast, upon treatment with myeloperoxidase, H2O2, and NaCl, the oxidized HiPco SWCNTs underwent complete oxidation (i.e., degradation). The shortened, NIR-fluorescent SWCNTs resulting from HRP-catalyzed oxidation of acid-cut HiPco SWCNTs may find applications in cellular NIR imaging and drug delivery systems.

Dates et versions

hal-00840159 , version 1 (01-07-2013)

Identifiants

Citer

Cheuk Fai Chiu, Brian A Barth, Gregg P Kotchey, Yong Zhao, Kristy A Gogick, et al.. Enzyme-Catalyzed Oxidation Facilitates the Return of Fluorescence for Single-Walled Carbon Nanotubes.. Journal of the American Chemical Society, 2013, epub ahead of print. ⟨10.1021/ja400699y⟩. ⟨hal-00840159⟩
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