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Communication Dans Un Congrès Année : 2012

Experimental ultrasound characterization of tissue-mimicking phantoms with high scatterer volume fractions

Résumé

Quantitative ultrasound technique is based on a frequency-based analysis of the signals backscattered from biological tissues. This technique aims to estimate the size and concentration of scatterers in order to diagnose and monitor diseases, such as cancer. The Gaussian Model (GM) and Fluid-Filled Sphere Model (FFSM) have been used for many years but are limited to dilute scattering medium, whereas the scatterers can be densely packed (for example the cells in cancer). A model adapted to dense medium is the Structure Factor model (SFM) used in blood characterization. However, the most often used SFM version is the Percus Yevick model (PYM) using the low frequency limit of the structure factor called the Percus Yevick packing factor. The aim of this work is to compare the aforementioned four scattering models with measured backscatter coefficients (BSCs) on tissue-mimicking phantoms. The tissue-mimicking phantoms consisted of polyamide microspheres (mean diameter 12 \mu m) immersed in agar-agar gel with different scatterer volume fractions ranging from 1 to 25%. Ultrasonic backscatter measurements were made for frequencies from 5 MHz to 22 MHz. For large scatterer volume fraction, the experimental BSCs agreed with predictions using the SFM in frequency dependence and scattering magnitude.
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Dates et versions

hal-00811017 , version 1 (23-04-2012)

Identifiants

  • HAL Id : hal-00811017 , version 1

Citer

Emilie Franceschini. Experimental ultrasound characterization of tissue-mimicking phantoms with high scatterer volume fractions. Acoustics 2012, Apr 2012, Nantes, France. ⟨hal-00811017⟩
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