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Communication Dans Un Congrès Année : 2005

Co-culture of cells in PDMS microsystem for sensitized artificial skin

Résumé

In this work a PDMS microsystem was conceived and fabricated for the development and study of an artificial skin-equivalent that includes nerve endings. A cellular coculture of keratinocytes, dorsal root ganglia neurons and spinal cord cells in microwells was developed. Microstructures were included in the microsystems, allowing infiltration of neuronal extensions to the skin-equivalent compartment. Electrophysiological measurements were conducted to measure electrical responses of the neurons in response to external stimulation of the skin.
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Dates et versions

hal-00795208 , version 1 (27-02-2013)

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L. Griscom, Y. Chateau, J. P. Pennec, Laurent Misery, Bruno Le Pioufle. Co-culture of cells in PDMS microsystem for sensitized artificial skin. 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, China. pp.184-187, ⟨10.1109/mmb.2005.1548421⟩. ⟨hal-00795208⟩
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