Wireless Sensor Network (WSN) are nowadays widely used in monitoring and tracking applications. This paper presents the feasibility of using Wireless Sensor Networks in active vibration control strategy. The active control method used is an active-structural acoustic control using piezoelectric sensors distributed on the car structure. This system aims at being merged in wireless sensor network whose head node collects data and process control law so as to command piezoelectric actuators wisely placed on the structure. We will study the feasibility of implementing WSN in active vibration control and introduce a complete design methodology to optimize hardware/software and control law synergy in mechatronic systems. A design space exploration will be conducted so as to identify the best Wireless Sensor Network platform and the resulting impact on control.