A tandem aza-Friedel-Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Tetrahedron Année : 2011

A tandem aza-Friedel-Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles

Résumé

A tandem aza-FriedeleCrafts reaction/Hantzsch cyclization is described to access various polysubstituted 2-amino-1,3-thiazoles from electron-rich (hetero)-aromatic rings, aldehydes, thiourea and a-chloroketones.

Dates et versions

hal-00783153 , version 1 (31-01-2013)

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Guilhem Chaubet, Ludovic T. Maillard, Jean Martinez, Nicolas Masurier. A tandem aza-Friedel-Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles. Tetrahedron, 2011, 67, pp.4987-4904. ⟨10.1016/j.tet.2011.04.090⟩. ⟨hal-00783153⟩
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