Candidoses associées aux cathéters : Quelle place pour les verrous antifongiques ? - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Médecine/Sciences Année : 2012

Could antifungal lock be useful in the management of candidiasis linked with catheters?

Candidoses associées aux cathéters : Quelle place pour les verrous antifongiques ?

Résumé

Fungal biofilms associated with inserted medical devices such as catheters, represent a major risk factor for candidemia. In addition, these biofilm yeasts show a decreased susceptibility to antifungal agents. Recently, a new therapeutic approach has emerged, the "lock therapy", based on the use of high concentrations of antimicrobials, instilled into the lumen of the catheter and left in place for 8 to 12 h. In vitro or in vivo studies have evaluated the interest of antifungal locks using amphotericin B, an azole or echinocandins. The promising results will permit us to discuss the relevance of this technique.

Dates et versions

hal-00763544 , version 1 (11-12-2012)

Identifiants

Citer

Estelle Cateau, Marie-Hélène Rodier, Christine Imbert. Candidoses associées aux cathéters : Quelle place pour les verrous antifongiques ?. Médecine/Sciences, 2012, 28 (8-9), pp.740-5. ⟨10.1051/medsci/2012288016⟩. ⟨hal-00763544⟩
86 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More