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Article Dans Une Revue Bioorganic and Medicinal Chemistry Année : 2010

Newoligo-β-(1,3)-glucan derivatives as immunostimulatingagents

Résumé

Oligo-β-(1,3)-glucans were chemically modified in order to introduce a structural variation specifically on the reducing end of the oligomers. The impact of well defined structural modulations was further studied on cancer cells and murin models to evaluate their cytotoxicity and immunostimulating potential.

Domaines

Chimie organique

Dates et versions

hal-00757226 , version 1 (26-11-2012)

Identifiants

Citer

Karine Descroix, Vaclav Vetvicka, Isabelle Laurent, Frank Jamois, Jean-Claude Yvin, et al.. Newoligo-β-(1,3)-glucan derivatives as immunostimulatingagents. Bioorganic and Medicinal Chemistry, 2010, 18 (1), pp.348-357. ⟨10.1016/j.bmc.2009.10.053⟩. ⟨hal-00757226⟩
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