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Communication Dans Un Congrès Année : 2012

Cortical networks involved in speech recovery after intra-oral surgery: an fMRI study

Résumé

Speech production after intra-oral surgery often requires the patient to go through a long speech recovery process. This study aims at better understanding the reorganization process of the control underlying the functional recovery of speech in patients after resection in the vocal tract region (i.e. carcinologic resection of mobile tongue, mouth floor and lips). In order to determine how the brain integrates new relationships between motor commands, auditory and oro-sensory feedbacks, we designed a longitudinal sparse-sampling fMRI study on 5 patients one week before and one month after surgery. One month after intra-oral resection, an increase of activity was observed in the supplementary motor area, the cingulate cortex, the globus pallidus (both involved in selection and initiation process suggesting more competitive mechanisms between motor strategies after surgery), the superior parietal lobule (somatosensory-motor control), the somatosensory and primary motor cortices (for proprioception and execution of movement). Additional patients are currently recruited and we expect the speech recovery process to be also associated with also significant activity changes in the cerebellum in relation with changes in motor plant. In our view and based on previous studies on internal models, cerebellar activity should be stronger during the first part of the process, as the results of the learning, before returning to a normal level in the second part. These preliminary results contribute to better understand the neural reorganization of sensory-motor structures associated with the speech production recovery process and brain mechanisms involved in relearning speech with a focus on internal model development and perceptuo-motor coupling.
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Dates et versions

hal-00747261 , version 1 (30-10-2012)

Identifiants

  • HAL Id : hal-00747261 , version 1

Citer

Audrey Acher, Marc Sato, Laurent Lamalle, Coriandre Emmanuel Vilain, Arnaud Attye, et al.. Cortical networks involved in speech recovery after intra-oral surgery: an fMRI study. NLC 2012 - 4th Annual Neurobiology of Language Conference, Oct 2012, San Sebastian, Spain. ⟨hal-00747261⟩
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