This work deals with the approximate reduction of a nonautonomous two time scales ordinary differential equations system with periodic fast dynamics. We illustrate this technique with the analysis of two models belonging to different fields in ecology. On the one hand, we deal with a two patches periodic predator-prey model with a refuge for prey. Considering migrations between patches to be faster than local interaction allows us to study a three-dimensional system by means of a two-dimensional one. On the other hand, a two time scales periodic eco-epidemic model is addressed by considering two competing species, one of them being affected by a periodic SIR epidemic process which is faster than inter-species interactions. The difference between time scales allows us to study the asymptotic behavior of the four-dimensional system by means of a planar, reduced one. Furthermore, we propose a methodology straightforwardly applicable to a very large class of two time scales periodic systems.