Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Mechanisms of Development Année : 1995

Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family.

Résumé

We have identified a new member of the elav gene family in Xenopus laevis. This gene, Xel-1, like the other elav-related genes, encodes a putative RNA-binding protein that contains three RNA Recognition Motifs and is solely expressed in the nervous system. Xel-1 is most likely the Xenopus homologue of Hel-N1, one of the three known human genes related to elav. Xel-1 is not expressed in early neural precursors but rather in differentiating neurons of the central nervous system, as well as in the cranial and the spinal ganglion cells. Xel-1 thus appears to be an early differentiation marker for both the central and the peripheral nervous system of Xenopus laevis.

Dates et versions

hal-00740599 , version 1 (10-10-2012)

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Muriel Perron, Laurent Théodore, Maurice Wegnez. Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family.. Mechanisms of Development, 1995, 51 (2-3), pp.235-49. ⟨10.1016/0925-4773(95)00368-1⟩. ⟨hal-00740599⟩
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