Structure and Charge-State Dependence of the Gas-Phase Ionization Energy of Proteins. - Archive ouverte HAL
Article Dans Une Revue Angewandte Chemie International Edition Année : 2012

Structure and Charge-State Dependence of the Gas-Phase Ionization Energy of Proteins.

Alexandre Giuliani
Aleksandar R Milosavljević
  • Fonction : Auteur
Francis Canon
Christophe Nicolas
  • Fonction : Auteur
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  • IdRef : 075098865
Matthieu Réfrégiers
Laurent Nahon

Résumé

Photoionization of protein ions: The ionization energy of polyprotonated protein cations in the gas phase measured using VUV synchrotron radiation appears to be correlated with the charge state z of the protein and its tertiary structure. A simple electrostatic model accounts for the results and also shows predictive capabilities to derive a mean radius R(m) of the protein ion from the ionization energy, and vice versa.

Dates et versions

hal-00727349 , version 1 (03-09-2012)

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Citer

Alexandre Giuliani, Aleksandar R Milosavljević, Konrad Hinsen, Francis Canon, Christophe Nicolas, et al.. Structure and Charge-State Dependence of the Gas-Phase Ionization Energy of Proteins.. Angewandte Chemie International Edition, 2012, 51, epub ahead of print. ⟨10.1002/anie.201204435⟩. ⟨hal-00727349⟩
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