Synthesis of new C-glycosyl aza-beta3-amino acids building blocks
Résumé
New C-glycosylated Nb-protected aza-beta3-amino acid building blocks have been prepared from C-glycosyl aldehydes of gluco and galacto configuration by reductive amination and subsequent N-alkylation. These moieties were elaborated to b-dipeptides by elongation at the C- or the N-terminus establishing their ability to be incorporated in original glycosylated foldamers.