Electrophilic Iodo-Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue SYNLETT Année : 2012

Electrophilic Iodo-Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles

Résumé

The rapid and facile synthesis of highly substituted β-iodofurans and β-iodopyrroles is reported using a mixture of molecular iodine and a base in solid PEG 3400 as alternative, eco-friendly and nontoxic solvent under microwave irradiation, in a very short time. The heterocycles are efficiently recovered in good yields by a simple workup procedure, avoiding chromatographic purification.
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Dates et versions

hal-00712937 , version 1 (28-06-2012)

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Citer

Rosella Spina, Evelina Colacino, Bartolo Gabriele, Giuseppe Salerno, Jean Martinez, et al.. Electrophilic Iodo-Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles. SYNLETT, 2012, pp.1481-1484. ⟨10.1055/s-0031-1291012⟩. ⟨hal-00712937⟩
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