Synthesis of tetraglucosyl- and tetrapolyamine-tetrabenzoporphyrin conjugates for an application in PDT. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Bioorganic and Medicinal Chemistry Année : 2009

Synthesis of tetraglucosyl- and tetrapolyamine-tetrabenzoporphyrin conjugates for an application in PDT.

Résumé

This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and MCF-7 and compared to Photofrin II.

Domaines

Chimie organique

Dates et versions

hal-00695882 , version 1 (10-05-2012)

Identifiants

Citer

Florian Ménard, Vincent Sol, Cyril Ringot, Robert Granet, Sandra Alves, et al.. Synthesis of tetraglucosyl- and tetrapolyamine-tetrabenzoporphyrin conjugates for an application in PDT.. Bioorganic and Medicinal Chemistry, 2009, 17 (22), pp.7647-57. ⟨10.1016/j.bmc.2009.09.048⟩. ⟨hal-00695882⟩
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