The enthalpies of solution (Dsol H) of carbon dioxide (CO2) in two aqueous solutions (w = 0.1500 and w = 0.3000) of monoethanolamine (MEA) have been measured at two temperatures (322.5 K and 372.9 K) and pressures up to 5 MPa. Measurements were carried out by a flow calorimetric technique using a custom-made flow-mixing unit combined with a SETARAM C-80 isothermal differential heat-flux calorimeter. Enthalpies of solution of CO2 (Dsol H) have been obtained as function of loading R (moles CO2/mol amine). Solubility data of the gas into the different absorbent (s) were derived from the enthalpic data.