Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Sexually Transmitted Infections Année : 2010

Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme

Penny A Cook
  • Fonction : Auteur
  • PersonId : 895336
Hannah Ce Madden
  • Fonction : Auteur
  • PersonId : 895337
Penelope A Phillips-Howard
  • Fonction : Auteur
  • PersonId : 895338
Stephen P Higgins
  • Fonction : Auteur
  • PersonId : 895339
Mark A Bellis
  • Fonction : Auteur
  • PersonId : 888309

Résumé

Background: The National Chlamydia Screening Programme in Greater Manchester (NCSP-GM) commissioned an evaluation of the management of gonorrhoea cases identified using the Gen-Probe APTIMA Combo 2 assay (AC2). Methods: NCSP-GM provided data on gonorrhoea cases from a six month period (September 2007-February 2008). We collected data from patient referral pathways to genitourinary medicine (GUM) clinics, including confirmatory testing, antibiotic resistance patterns and contact tracing. The AC2 positive predictive value (PPV) was calculated. Results: 111 individuals tested positive for gonococcal infection using AC2 (0.7% of 16,028 individuals tested). Of these, 96 (0.6% of all tested) known index cases were seen at Greater Manchester GUM clinics. 78/96 (14 males, 64 females) underwent confirmatory microscopy and gonococcal culture. Confirmatory tests were positive in 14 males (100%) but only 40 females (78%). Thus the PPV of AC2 was 69% (54/78). Sensitivity in women may have been reduced by limited partner information and sample-taking (only 28% had a full gonorrhoea screen). Conclusion: Gonorrhoea screening in an NCSP-targeted population identified gonorrhoea in a low-risk population. Subsequent management in GUM clinics was variable and limited sample-taking may have decreased the sensitivity of confirmatory testing in women. Appropriate antibiotic sensitivity tests or, in their absence, a test of cure may be needed to ensure effective treatment.
Fichier principal
Vignette du fichier
PEER_stage2_10.1136%2Fsti.2010.043240.pdf (105.59 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-00576098 , version 1 (12-03-2011)

Identifiants

Citer

Jennifer Downing, Penny A Cook, Hannah Ce Madden, Penelope A Phillips-Howard, Stephen P Higgins, et al.. Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme. Sexually Transmitted Infections, 2010, 86 (6), pp.474. ⟨10.1136/sti.2010.043240⟩. ⟨hal-00576098⟩

Collections

PEER
35 Consultations
91 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More