Methods of sonification based on the design and control of sound synthesis is presented in this pa- per. The semiotics of isolated sounds was evidenced by performing fundamental studies using a combined acoustical and brain imaging (Event Related Poten- tials) approach. The perceptual cues (which are known as invariants) responsible for the evocations elicited by the sounds generated by impacts, moving sound sour- ces, dynamic events and vehicles (car-door closing and car engine noise) were then identified based on physical and perceptual considerations. Lastly, some examples of the high-level control of a synthesis process simulat- ing immersive 3-D auditory scenes, interacting objects and evoked dynamics are presented.