Genetic characterization of G3 rotaviruses detected in Italian children in the years 1993-2005 - Archive ouverte HAL Access content directly
Journal Articles Journal of Medical Virology Year : 2009

Genetic characterization of G3 rotaviruses detected in Italian children in the years 1993-2005

Abstract

In recent years an apparent increase in the frequency of detection of G3P[8] rotaviruses has been observed worldwide. Similarly, in Italy G3P[8] strains have been detected sporadically and in a scattered fashion over 20 years, whereas in 2003 and 2005 G3P[8] rotavirus activity increased markedly. By analysis of the VP7, VP4, VP6 and NSP4 genes of a selection of G3P[8] rotaviruses detected between 1993 and 2005, a remarkable sequence conservation was observed in the VP7, VP4 and VP6 genes. By converse, after 2002 the Italian G3P[8] strains were found to possess unique mutations in significant regions of the NSP4 protein.

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Dates and versions

hal-00531824 , version 1 (04-11-2010)

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Simona de Grazia, Vito Martella, Claudia Colomba, Antonio Cascio, Serenella Arista, et al.. Genetic characterization of G3 rotaviruses detected in Italian children in the years 1993-2005. Journal of Medical Virology, 2009, 81 (12), pp.2089. ⟨10.1002/jmv.21615⟩. ⟨hal-00531824⟩

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