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Article Dans Une Revue Journal of Molecular Endocrinology Année : 2010

Adrenocortical development and cancer: focus on SF-1.

Résumé

Steroidogenic factor-1 (SF-1/Ad4-binding protein; NR5A1) is an essential regulator of tissue-specific gene expression in steroidogenic cells and of adrenogonadal development. Here, I discuss recent data in the literature showing the implication of SF-1 and the importance of its dosage not only during development but also for adrenal cortex tumorigenesis in humans and mice.

Domaines

Cancer

Dates et versions

hal-00497715 , version 1 (05-07-2010)

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Citer

Enzo Lalli. Adrenocortical development and cancer: focus on SF-1.. Journal of Molecular Endocrinology, 2010, 44 (6), pp.301-7. ⟨10.1677/JME-09-0143⟩. ⟨hal-00497715⟩
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