Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3 - Archive ouverte HAL Access content directly
Journal Articles Biochemical Pharmacology Year : 2009

Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3

Agnes Leffler
  • Function : Author
Ingela Ahlstedt
  • Function : Author
Susanna Engberg
  • Function : Author
Arne Svensson
  • Function : Author
Martin Billger
  • Function : Author
Lisa Öberg
  • Function : Author
Magnus Bjursell
  • Function : Author
Erik Lindström
  • Function : Author
Bengt von Mentzer
  • Function : Correspondent author
  • PersonId : 872312

Connectez-vous pour contacter l'auteur

Abstract

Tachykinin NK receptors (NKR) differ to a large degree among species with respect to their affinities for small molecule antagonists. The aims of the present study were to clone NKRs from gerbil (NKR and NKR) and dog (NKR, NKR, NKR) in which the sequence was previously unknown and to investigate the potency of several NKR antagonists at all known human, dog, gerbil and rat NKRs.
Fichier principal
Vignette du fichier
PEER_stage2_10.1016%2Fj.bcp.2009.01.020.pdf (782.53 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-00493489 , version 1 (19-06-2010)

Identifiers

Cite

Agnes Leffler, Ingela Ahlstedt, Susanna Engberg, Arne Svensson, Martin Billger, et al.. Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3. Biochemical Pharmacology, 2009, 77 (9), pp.1522. ⟨10.1016/j.bcp.2009.01.020⟩. ⟨hal-00493489⟩

Collections

PEER
24 View
380 Download

Altmetric

Share

Gmail Facebook X LinkedIn More