Article Dans Une Revue Nano Letters Année : 2009

Nanowire biocompatibility in the brain - Looking for a needle in a 3D stack

Résumé

We investigated the brain-tissue response to nanowire implantations in the rat striatum after 1, 6, and 12 weeks using immunohistochemistry. The nanowires could be visualized in the scar by confocal microscopy (through the scattered laser light). For the nanowire-implanted animals, there is a significant astrocyte response at week 1 compared to controls. The nanowires are phagocytized by ED1 positive microglia, and some of them are degraded and/or transported away from the brain.

Fichier non déposé

Dates et versions

hal-00471929 , version 1 (09-04-2010)

Identifiants

Citer

Cecilia Eriksson-Linsmeier, Christelle Prinz, Lina M. E. Pettersson, Philippe Caroff, Lars Samuelson, et al.. Nanowire biocompatibility in the brain - Looking for a needle in a 3D stack. Nano Letters, 2009, 9 (12), pp.4184–4190. ⟨10.1021/nl902413x⟩. ⟨hal-00471929⟩
65 Consultations
0 Téléchargements

Altmetric

Partager

  • More