Taste, movement, and death: varying effects of new prospero mutants during Drosophila development - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Neurobiology Année : 2003

Taste, movement, and death: varying effects of new prospero mutants during Drosophila development

Résumé

The PGal4 transposon inserted upstream of the pan-neural gene prospero (pros) causes several neural and behavioral defects in the Voila(1) strain. The precise excision of the transposon simultaneously rescued all these defects whereas its unprecise excision created new pros(V) alleles, including the null allele pros(V17). Here, we describe the relationship between the genetic structure of pros locus, larval locomotion, and larval gustatory response. These two behaviors showed varying degrees of variation depending upon the pros allele. We also found a good relation between behavioral alteration, the level of Pros protein in the embryo, and the degree of disorganization in the larval neuromuscular junction. These data suggest that the complete development of the nervous system requires a full complement of Pros, and that a gradual decrease in the levels of this protein can proportionally alter the development and the function of the nervous system.
Fichier non déposé

Dates et versions

hal-00451459 , version 1 (29-01-2010)

Identifiants

  • HAL Id : hal-00451459 , version 1

Citer

Yaël Grosjean, Fabien Lacaille, Angel Acebes, J. Clemencet, Jean-François Ferveur. Taste, movement, and death: varying effects of new prospero mutants during Drosophila development. Journal of Neurobiology, 2003, 55 (1), pp.1-13. ⟨hal-00451459⟩
39 Consultations
0 Téléchargements

Partager

Gmail Facebook X LinkedIn More