POGG: Integrating qualitative and quantitative data of macromolecular networks. A probabilistic toolbox
Résumé
POGG (Probabilities On Genetic Graphs) is a software dedicated to the study of stochastic graph. It implements an original method based on the theory of average-case analysis of algorithms. It builds constraints between biological observations and classical constants of an undetermined weighted stochastic model. With these constraints, the software provides a fully determined model that (1) is coherent with observations; (2) allows to simulate unobserved quantities, even with a minimal information on them; (3) permits to reason on the system because it predicts local impacts of every transitions on the global behavior of the living system.