Article Dans Une Revue Acta Crystallographica Section F: Structural Biology and Crystallization Communications Année : 2008

Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase

Résumé

The 716-amino-acid guanidino kinase from the parasitic flatworm Schistosoma mansoni results from the fusion of two guanidino kinase subunits. Crystals of this 80 kDa protein have been obtained in the monoclinic space group P2(1), with unit-cell parameters a = 52.7, b = 122.1, c = 63.2 A, beta = 108.5 degrees . Synchrotron data were collected to 2.8 A resolution on ESRF beamline ID29. The structure was solved by the molecular-replacement method, using the 357-amino-acid structure of the arginine kinase from Trypanosoma cruzi as the search model.

Dates et versions

hal-00445416 , version 1 (08-01-2010)

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Citer

Ayman M. Awama, Patricia Paracuellos, Sabine Laurent, Colette Dissous, Olivier Marcillat, et al.. Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2008, 64 (9), pp.854-857. ⟨10.1107/S1744309108025979⟩. ⟨hal-00445416⟩
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